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de Vries, J, Monteiro, FM, Langer, G, Brownlee, C and Wheeler, G 2024 A critical trade-off between nitrogen quota and growth allows Coccolithus braarudii life cycle phases to exploit varying environment. Biogeosciences, 21 (7). 1707-1727. https://doi.org/10.5194/bg-21-1707-2024
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Keys, M, Hopkinson, B, Highfield, A, Chrachri, A, Brownlee, C and Wheeler, G 2023 The requirement for external carbonic anhydrase in diatoms is influenced by the supply and demand for dissolved inorganic carbon. Journal of Phycology. https://doi.org/10.1111/jpy.13416
Sturm, D, de Vries, J, Balch, WM, Wheeler, G and Brownlee, C 2023 Mesoscale oceanographic meanders influence protist community function and structure in the southern Indian Ocean. Environmental Microbiology. https://doi.org/10.1111/1462-2920.16500
Brownlee, C and Wheeler, G 2023 Spatiotemporal cytosolic Ca2+ signals in plants and algae: divergent means to an end. Bioelectricity, 5 (1). https://doi.org/10.1089/bioe.2023.0004
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Brownlee, C, Wheeler, G, Ratcliffe, S, Meyer, EM, Walker, CE, Knight, M, McNair, HM, Matson, PG, Iglesias-Rodriguez, D and Langer, G 2023 Characterization of the molecular mechanisms of silicon uptake in coccolithophores. Environmental Microbiology, 25 (2). 315-330. https://doi.org/10.1111/1462-2920.16280
Brownlee, C, Helliwell, KE, Meeda, Y, McLachlan, D, Murphy, EA and Wheeler, G 2023 Regulation and integration of membrane transport in marine diatoms [in special issue: Algal model organisms by Susana Coelho and Olivier de Clerck] Seminars in cell & developmental biology, 134. 79-89. https://doi.org/10.1016/j.semcdb.2022.03.006
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Ramos, JBE, Ribeiro, SC, Schulz, KG, Coelho, FJRD, Oliveira, V, Cunha, A, Gomes, NCM, Brownlee, C, Passow, U and Azevedo, EB 2022 Emiliania huxleyi: bacteria interactions under increasing CO2 concentrations [in special issue: A Glimpse into Future Research on Microalgae Diversity, Ecology and Biotechnology] Microorganisms, 10 (12). https://doi.org/10.3390/microorganisms10122461
Langer, G, Probert, I, Cox, MB, Taylor, A, Harper, GM, Brownlee, C and Wheeler, G 2022 The effect of cytoskeleton inhibitors on coccolith morphology in Coccolithus braarudii and Scyphosphaera apsteinii. Journal of Phycology.
Brownlee, C 2022 Dr Quentin Bone, 1931–2021. Journal of the Marine Biological Association of the United Kingdom, 102 (6). 457-458.
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Brownlee, C 2022 Plant physiology; anatomy of a plant action potential. Current Biology, 32 (19). R1000-R1002. https://doi.org/10.1016/j.cub.2022.08.024
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Kleiner, FH, Helliwell, KE, Chrachri, A, Hopes, A, Parry-Wilson, H, Gaikwad, T, Mieszkowska, N, Mock, T, Wheeler, GL and Brownlee, C 2022 Cold-induced [Ca2+]cyt elevations function to support osmoregulation in marine diatoms. Plant Physiology, kiac324. https://doi.org/10.1093/plphys/kiac324
Kottmeier, DM, Chrachri, A, Langer, G, Helliwell, KE, Wheeler, G and Brownlee, C 2022 Reduced H+ channel activity disrupts pH homeostasis and calcification in coccolithophores at low ocean pH. Environmental Sciences, 119 (19), e211800911. 11, pp. https://doi.org/10.1073/pnas.2118009119
Langer, G, Jie, VW, Kottmeier, D, Flori, S, Sturm, D, de Vries, J, Harper, GM, Brownlee, C and Wheeler, G 2022 Distinct physiological responses of Coccolithus braarudii life cycle phases to light intensity and nutrient availability. European Journal of Phycology. https://doi.org/10.1080/09670262.2022.2056925
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Wheeler, G, Taylor, AR and Brownlee, C 2021 CELLULAR MECHANISMS UNDERLYING THE RESPONSE OF COCCOLITHOPHORES TO FUTURE CHANGES IN OCEAN CARBONATE CHEMISTRY. Phycologia, 60. 56.
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Sturm, D, Wheeler, G, Brownlee, C and Tyrrell, T 2021 EXAMINING THE PHYSIOLOGY AND BIOGEOGRAPHY OF COCCOLITHOPHORE LIFE CYCLE STAGES. Phycologia, 60. 83.
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Helliwell, KE, Kleiner, FH, Hardstaff, Hayley, Chrachri, A, Gaikwad, T, Salmon, D, Smirnoff, N, Wheeler, G and Brownlee, C 2021 Spatiotemporal patterns of intracellular Ca2+ signalling govern hypo-osmotic stress resilience in marine diatoms. New Phytologist, 230 (1). 155-170. https://doi.org/10.1111/nph.17162
Langer, G, Taylor, AR, Walker, CE, Meyer, EM, Joseph, OB, Gal, A, Harper, GM, Probert, I, Brownlee, C and Wheeler, G 2021 Role of silicon in the development of complex crystal shapes in coccolithophores. New Phytologist, 231 (5). 1845-1857. https://doi.org/10.1111/nph.17230
Helliwell, KE, Harrison, EL, Christie-Oleza, JA, Rees, AP, Kleiner, FH, Gaikwad, T, Downe, J, Aguilo-Ferretjans, MM, Al-Moosawi, L, Brownlee, C and Wheeler, GL 2020 A Novel Ca2+ Signaling Pathway Coordinates Environmental Phosphorus Sensing and Nitrogen Metabolism in Marine Diatoms. Current Biology, 31. 1-12. https://doi.org/10.1016/j.cub.2020.11.073
Kottmeier, D, Chrachri, A, Langer, G, Wheeler, G and Brownlee, C 2020 Differences in acid-base regulation of haploid and diploid life-cycle stages of Coccolithus braarudii and their consequences for the sensitivity towards ocean acidification. Access Microbiology, 2 (7A). https://doi.org/10.1099/acmi.ac2020.po0749
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Fort, C, Collingridge, P, Brownlee, C and Wheeler, G 2020 Ca2+ elevations disrupt interactions between intraflagellar transport and the flagella membrane in Chlamydomonas. Journal of Cell Science, 134 (3). https://doi.org/10.1242/jcs.253492
Brownlee, C 2018 Plant Physiology: One Way to Dump Salt. Current Biology, 28 (19). R1145-R1147. https://doi.org/10.1016/j.cub.2018.08.062
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Walker, CE, Taylor, AR, Langer, G, Durak, GM, Heath, S, Probert, I, Tyrrell, T, Brownlee, C and Wheeler, GL 2018 The requirement for calcification differs between ecologically important coccolithophore species. New Phytologist. https://doi.org/10.1111/nph.15272
Wheeler, G, Helliwell, KE and Brownlee, C 2018 Calcium signalling in algae. Perspectives in Phycology. https://doi.org/10.1127/pip/2018/0082
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Brownlee, C 2018 Stomatal Physiology: Cereal Successes. Current Biology, 28 (9). R551-R553. https://doi.org/10.1016/j.cub.2018.03.055
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Chrachri, A, Hopkinson, BM, Flynn, KJ, Brownlee, C and Wheeler, G 2018 Dynamic changes in carbonate chemistry in the microenvironment around single marine phytoplankton cells. Nature Communications, 9 (1). https://doi.org/10.1038/s41467-017-02426-y
Durak, GM, Brownlee, C and Wheeler, G 2017 The role of the cytoskeleton in biomineralisation in haptophyte algae. Scientific Reports, 7 (1). https://doi.org/10.1038/s41598-017-15562-8
Brownlee, C 2017 Plant Physiology: The Venus Flytrap Counts on Secretion. Current Biology, 27 (15). R763-R764. https://doi.org/10.1016/j.cub.2017.06.029
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McKeown, DA, Stevens, K, Peters, AF, Bond, P, Harper, GM, Brownlee, C, Brown, MT and Schroeder, DC 2017 Phaeoviruses discovered in kelp (Laminariales). The ISME Journal, 11 (12). 2869-2873. https://doi.org/10.1038/ismej.2017.130
Edel, KH, Marchadier, E, Brownlee, C, Kudla, J and Hetherington, AM 2017 The Evolution of Calcium-Based Signalling in Plants. Current Biology, 27 (13). R667-R679. https://doi.org/10.1016/j.cub.2017.05.020
Taylor, AR, Brownlee, C and Wheeler, G 2016 Coccolithophore Cell Biology: Chalking Up Progress. Annual Review of Marine Science, 9 (1). 283-310. https://doi.org/10.1146/annurev-marine-122414-034032
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Taylor, AR, Brownlee, C and Wheeler, G 2016 Coccolithophore Cell Biology: Chalking Up Progress. Annual Review of Marine Science, 9 (1). 283-310. https://doi.org/10.1146/annurev-marine-122414-034032
Bickerton, P, Sello, S, Brownlee, C, Pittman, JK and Wheeler, GL 2016 Spatial and temporal specificity of Ca2+signalling inChlamydomonas reinhardtiiin response to osmotic stress. New Phytologist. https://doi.org/10.1111/nph.14128
Monteiro, FM, Bach, LT, Brownlee, C, Bown, P, Rickaby, REM, Poulton, AJ, Tyrrell, T, Beaufort, L, Dutkiewicz, S, Gibbs, SW, Gutowska, MA, Lee, R, Riebesell, U, Young, J and Ridgwell, AJ 2016 Why marine phytoplankton calcify. Science Advances, 2 (7). e1501822-e1501822. https://doi.org/10.1126/sciadv.1501822
Brownlee, C and Taylor, AR 2016 Calcification. In: Borowitzka, MA; Beardall, J; Raven, JA, (eds.) The Physiology of Microalgae. Springer International Publishing, 301-308, 8pp. (Developments in Applied Phycology, 8).
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Rickaby, REM, Hermoso, M, Lee, RBY, Rae, BD, Heureux, AMC, Balestreri, C, Chakravarti, L, Schroeder, DC and Brownlee, C 2016 Environmental carbonate chemistry selects for phenotype of recently isolated strains of Emiliania huxleyi. Deep Sea Research Part II: Topical Studies in Oceanography, 127. 28-40. https://doi.org/10.1016/j.dsr2.2016.02.010
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Koester, J, Brownlee, C and Taylor, AR 2016 Algal Calcification and Silicification. In: eLS. John Wiley & Sons, 1-10.
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Durak, GM, Taylor, AR, Walker, CE, Probert, I, de Vargas, C, Audic, S, Schroeder, DC, Brownlee, C and Wheeler, G 2016 A role for diatom-like silicon transporters in calcifying coccolithophores.. Nature communications, 7. 10543. https://doi.org/10.1038/ncomms10543
Brownlee, C, Wheeler, G and Taylor, AR 2015 Coccolithophore biomineralization: New questions, new answers.. Seminars in cell & developmental biology, 46. 11-6. https://doi.org/10.1016/j.semcdb.2015.10.027
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Flynn, KJ, Clark, DR, Mitra, A, Fabian, H, Hansen, PJ, Glibert, PM, Wheeler, GL, Stoecker, DK, Blackford, JC and Brownlee, C 2015 Ocean acidification with (de)eutrophication will alter future phytoplankton growth and succession.. Proceedings. Biological sciences / The Royal Society, 282 (1804). 20142604. https://doi.org/10.1098/rspb.2014.2604
Krueger-Hadfield, SA, Balestreri, C, Schroeder, J, Highfield, A, Helaouët, P, Allum, J, Moate, R, Lohbeck, KT, Miller, PI, Riebesell, U, Reusch, TBH, Rickaby, REM, Young, J, Hallegraeff, G, Brownlee, C and Schroeder, DC 2014 Genotyping an Emiliania huxleyi (prymnesiophyceae) bloom event in the North Sea reveals evidence of asexual reproduction. Biogeosciences, 11 (18). 5215-5234. https://doi.org/10.5194/bg-11-5215-2014
Brodie, J, Williamson, CJ, Smale, DA, Kamenos, NAK, Mieszkowska, N, Santos, RS, Cunliffe, M, Steinke, M, Yesson, C, Anderson, KM, Asnaghi, V, Brownlee, C, Burdett, HL, Burrows, MT, Collins, S, Donohue, PJC, Harvey, B, Foggo, A, Noisette, F, Nunes, J, Ragazzola, F, Raven, JA, Schmidt, DN, Suggett, D, Teichberg, M and Hall-Spencer, JM 2014 The future of the northeast Atlantic benthic flora in a high CO2 world. Ecology and Evolution, 4 (13). 2787-2798. https://doi.org/10.1002/ece3.1105
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Stevens, K, Weynberg, KD, Bellas, C, Brown, S, Brownlee, C, Brown, MT and Schroeder, DC 2014 A novel evolutionary strategy revealed in the phaeoviruses. PLoS one, 9 (1).
Collingridge, P, Brownlee, C and Wheeler, GL 2013 Compartmentalized Calcium Signaling in Cilia Regulates Intraflagellar Transport. Current Biology, 23 (22). 2311-2318. https://doi.org/10.1016/j.cub.2013.09.059
Bach, L, Mackinder, L, Schulz, K, Wheeler, G, Schroeder, DC, Brownlee, C and Riebesell, U 2013 Dissecting the impact of CO2 and pH on the mechanisms of photosynthesis and calcification in the coccolithophore Emiliania huxleyi. New Phytologist, 199 (1). 121 - 134. https://doi.org/10.1111/nph.12225
Brownlee, C, Chrachri, A, Taylor, AR, Balestreri, C, Krueger-Hadfield, S and Wheeler, G 2013 Understanding the Mechanisms of Cell and Population Responses of Coccolithophores to Changing Ocean Chemistry. In: UNSPECIFIED. 14.
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Depledge, MH, Harvey, AJ, Brownlee, C, Frost, MT, Moore, MN and Fleming, LE 2013 Changing Views of the Interconnections Between the Oceans and Human Health in Europe. Microbial Ecology, 65. 248 - 255. https://doi.org/10.1007/s00248-012-0173-0
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Williamson, P, Turley, CM, Brownlee, C, Findlay, HS, Ridgwell, AJ, Schmidt, DN, Schroeder, DC, Blackford, JC, Tyrrell, T and Pinnegar, JK 2013 Impacts of ocean acidification. MCCIP. 1-16.
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Taylor, AR, Brownlee, C and Wheeler, G 2012 Proton channels in algae: reasons to be excited. Trends in Plant Science, 17. 675 - 684. https://doi.org/10.1016/j.tplants.2012.06.009
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Flynn, KJ, Blackford, JC, Baird, ME, Raven, J, Clark, DR, Beardall, J, Brownlee, C, Fabian, H and Wheeler, G 2012 Changes in pH at the exterior surface of plankton with ocean acidification. Nature Climate Change, 2. 510 - 513. https://doi.org/10.1038/nclimate1489
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Mackinder, L, Wheeler, G, Schroeder, DC, Von Dassow, P, Riebesell, U and Brownlee, C 2011 Expression of biomineralization-related ion transport genes in Emiliania huxleyi. Environmental Microbiology, 13(12). 3250 - 3265. https://doi.org/10.1111/j.1462-2920.2011.02561.x
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Brownlee, C, Taylor, A, Wheeler, G and Chrachri, A 2011 Ion Channels Signalling and Cellular Function in Algae: Clues on the Origins of Excitability in Eukaryotes. European Journal of Phycology, 46. 31 - 31.
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Salmon, D, Smirnoff, N, Wheeler, G and Brownlee, C 2011 Metabolite Profiling Indicates Intraspecific Variability in the Accumulation of Compatible Solutes in the Haptophyte Alga Emiliania Huxleyi. European Journal of Phycology, 46. 154 - 155.
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Taylor, AR, Chrachri, A, Wheeler, G, Goddard, H and Brownlee, C 2011 A voltage-gated H+ channel underlying pH homeostasis in calcifying coccolithophores. PLoS Biology, 6. 01-Jan. https://doi.org/10.1371/journal.pbio.1001085
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Taylor, AR, Chrachri, A, Wheeler, G, Goddard, H and Brownlee, C 2011 Proton Conductance in Coccolithophores Is an Integral Component of Ph Homeostasis During Calcification. Journal of Phycology, 47. 27 - 27.
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Turley, CM, Brownlee, C, Findlay, HS, Mangi, SC, Ridgwell, AJ, Schmidt, DN and Schroeder, DC 2010 Ocean Acidification in MCCIP Annual Report Card 2010-11. [Output (Electronic)]
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Mackinder, L, Wheeler, G, Schroeder, DC, Riebesell, U and Brownlee, C 2010 Molecular Mechanisms Underlying Calcification in Coccolithophores. Geomicrobiology Journal, 27. 585 - 595. https://doi.org/10.1080/01490451003703014
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Turley, CM, Eby, M, Ridgwell, AJ, Schmidt, DN, Findlay, HS, Brownlee, C, Riebesell, U, Fabry, VJ and Feely, RA 2010 The societal challenge of ocean acidification. Marine Pollution Bulletin, 60. 787 - 792. https://doi.org/10.1016/j.marpolbul.2010.05.006
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Verret, F, Wheeler, G, Taylor, AR, Farhham, G and Brownlee, C 2010 Calcium channels in photosynthetic eukaryotes: implications for evolution of calcium-based signalling. New Phytologist, 187. 23 - 43. https://doi.org/10.1111/j.1469-8137.2010.03271.x
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Ridgwell, AJ, Schmidt, DN, Turley, CM, Brownlee, C, Maldonado, MT, Tortell, P and Young, JR 2009 From laboratory manipulations to Earth system models: scaling calcification impacts of ocean acidification. Biogeosciences, 11. 2611 - 2623.
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Wheeler, G and Brownlee, C 2008 Ca2+ signalling in plants and green algae - changing channels. Trends in Plant Science, 13. 506 - 514. https://doi.org/10.1016/j.tplants.2008.06.004
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Wheeler, G, Joint, IR and Brownlee, C 2008 Rapid spatiotemporal patterning of cytosolic Ca2+ underlies flagellar excision in Chlamydomonas reinhardtii. Plant Journal, 53. 401 - 413. https://doi.org/10.1111/j.1365-313X.2007.03349.x
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Thompson, SEM, Callow, JA, Callow, ME, Wheeler, G, Taylor, AR and Brownlee, C 2007 Membrane Recycling And Calcium Dynamics During Settlement And Adhesion Of Zoospores Of The Green Alga Ulva Linza. UNSPECIFIED, 733 - 744.
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Wheeler, G, Tait, K, Taylor, AR, Brownlee, C and Joint, IR 2006 Acyl-homoserine lactones modulate the settlement rate of zoospores of the marine alga Ulva intestinalis via a novel chemokinetic mechanism. UNSPECIFIED, 608 - 618.
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Bothwell, JHF, Brownlee, C, Hetherington, AM, Ng, CK, Wheeler, G and McAinsh, MR 2006 Biolistic delivery of Ca2+ dyes into plant and algal cells. Plant Journal, 46(2). 327 - 335. https://doi.org/10.1111/j.1365-313X.2006.02687.x
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Sanders, D, Pelloux, J, Brownlee, C and Harper, JF 2002 Calcium at the crossroads of signalling. Plant Cell, 14. S401-S417.
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Coelho, S, Taylor, AR, Ryan, KP, Sousa-Pinto, I, Brown, MT and Brownlee, C 2002 Spatio-temporal patterning of reactive oxygen production and Ca2+ wave propagation in Fucus rhizoid cells. Plant Cell, 14. 1-15.
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Corellou, F, Brownlee, C, Detivaud, L, Kloareg, B and Bouget, F-Y 2001 Cell cycle in the Fucus zygote parallels a somatic cell cycle but displays a unique translational regulation of cyclin-dependent kinases. Plant Cell, 13. 585-598.
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Goddard, H, Manison, NFH, Tomos, D and Brownlee, C 2000 Elemental propagation of calcium signals in response-specific patterns determined by environmental stimulus strength. Proceedings of the National Academy of Sciences of the United States of America, 97. 1932-1937.
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Pond, DW, Harris, RP and Brownlee, C 1995 A Microinjection Technique Using A pH-Sensitive Dye To Determine The Gut pH Of Calanus-Helgolandicus. Marine Biology, 123 (1). 75 - 79. https://doi.org/10.1007/BF00350325
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Westbroek, P, Brown, CW, Vanbleijswijk, J, Brownlee, C, Brummer, GJ, Conte, MH, Egge, JK, Fernandez, E, Jordan, R, Knappertsbusch, M, Stefels, J, Veldhuis, M, Vanderwal, P and Young, J 1993 A Model System Approach To Biological Climate Forcing - The Example Of Emiliania-Huxleyi. Global and Planetary Change, 8 (01-Feb). 27 - 46. https://doi.org/10.1016/0921-8181(93)90061-R
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Brownlee, C, Wood, JW and Briton, D 1987 Cytoplasmic Free Calcium In Single Cells Of Centric Diatoms - The Use Of Fura-2. Protoplasma, 140 (02-Mar). 118 - 122. https://doi.org/10.1007/BF01273720
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