Genome Sequence Databases: Types of Data and Bioinformatic Tools

Gutiérrez-Preciado, A, Deschamps, P, O.Delmont, T, Chica, C, Chrismas, N and Rodríguez de la Vega, RC 2019 Genome Sequence Databases: Types of Data and Bioinformatic Tools. Encyclopedia of Microbiology (Fourth Edition). 419-427. https://doi.org/10.1016/B978-0-12-801238-3.99223-7

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Abstract/Summary

In a little more than a decade, we have transitioned from an era where DNA sequences were visually “read” on painstakingly prepared electrophoresis gels by specialized laboratories to “read” the sequence by literally threading millions of individual DNA molecules through millions of macromolecular pores in a cellphone-sized device connected to a computer through USB right in the sampling field. This blooming of sequences has unveiled a previously hidden diversity that has impressively expanded and entangled our view of the tree of life. Bioinformatic tools and public databases have been developed to support the analysis of sequence data that has radically increased in the last decade. In this article, we provide a brief overview of such tools and resources and exemplify how these could be used to decipher the microbial inhabitants of any ecosystem and understand what they are doing in the environment.

Item Type:	Publication - Article
Additional Keywords:	Bioinformatic databases Comparative genomics Genome analysis Genome binning High-throughput sequencing Metabarcoding Metagenome-assembled genomes (MAGs)Metagenomics Microbial diversity Pangenomics Phylogenomics Sequence repositories Single-cell amplified genomes (SAGs)Tree of life
Subjects:	Marine Sciences
Divisions:	Marine Biological Association of the UK > Marine Microbiome
Depositing User:	Emily Smart
Date made live:	08 Oct 2021 13:52
Last Modified:	09 Feb 2024 17:07
URI:	https://plymsea.ac.uk/id/eprint/9401

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