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Moore, MN and Stebbing, ARD 1976 Quantitative Cytochemical Effects Of 3 Metal-Ions On A Lysosomal Hydrolase Of A Hydroid. Journal of the Marine Biological Association of the United Kingdom, 56 (4). 995 -1005. https://doi.org/10.1017/S0025315400021032
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Moore & Stebbing J Mar Biol Ass UK 1976.pdf Download (1MB) | Preview |
Abstract/Summary
The quantitative effects of Cu8+, Cd2+ and Hg2+ on the cytochemical staining reaction for lysosomal N-acetyl-/?-D-glucosaminidase have been determined and related to the inhibitory effects of the metals on colonial growth rate in the experimentally cultured hydroid Campanularia flexuosa. Cytochemical threshold concentrations are comparable to known environmental levels and are about one order of magnitude lower than those obtained by measuring colony growth rates. Pretreatment of colonies with Cuz+ gave no indication of tolerance adaptation, although there is evidence of the cumulative toxicity of Cu2+ and the possible sequestration of this metal in endodermal cell lysosomes. There is also an indication that the Cu2+ may exert its toxic effect by decreasing the stability of the lysosomal membranes, thus increasing the level of free glucosaminidase activity.
| Item Type: | Publication - Article |
|---|---|
| Divisions: | Plymouth Marine Laboratory > Other (PML) |
| Depositing User: | EPrints Services |
| Date made live: | 11 Feb 2014 15:54 |
| Last Modified: | 25 Apr 2020 09:56 |
| URI: | https://plymsea.ac.uk/id/eprint/2856 |
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